Welcome to the Thomson Lab

Our Focus

Healthy skeletal muscles are incredibly dynamic organs that are capable of adapting to a wide range of mechanical and metabolic stressors. For instance, repetitive loading leads to muscle growth, or hypertrophy, while disuse results in a loss of muscle size, or atrophy. Like most tissues in the body, skeletal muscle is also capable of repairing itself after damaging injury. Unfortunately, these processes of growth and repair often become short-circuited in old-age.

In my laboratory, our primary research interest is to understand what causes age-related muscle dysfunction. Understanding the mechanisms that control muscle dysfunction will be important in developing behavioral and pharmacological treatments for conditions where muscle mass is compromised. We are particularly interested in the loss of old muscle’s ability to maintain or increase its size and to repair itself after injury. Secondarily, since we view insulin resistance (an underlying cause of type II diabetes) as a premature aging-condition (old and insulin-resistant muscles exhibit very similar dysfunctions), we are also interested in the regulation of muscle size and repair in obesity and diabetes. 

     

Email: david_thomson@byu.edu

3013  LSB
Provo, UT 84602
(801) 422-8709

Associate Professor

Curriculum Vitae